ABSTRACT
Sex-cord stromal tumors of ovary account for 5~8% of all ovarian malignancies. This group of ovarian neoplasms is derived from the sex cords and the ovarian stroma or mesenchyme. Although they can occur in women of all ages, they tend to have peak incidence in those over age50. So they should be surgically managd with hysterectomy and bilateral salpingo-oophorectomy. The purpose of this study is to report the experience at Asan Medical Center, Department of Obstetrics and Gynecology, in 24 patients with ovarian sex-cord stromal tumortreated between May, 1989 and April, 1995. We analyzed the effect of histologic subtype, FIGO stage, age and management. The results were as follows: 1. In histologic subtypes, fibrothecoma(66.7%), granulosa cell tumor(20.8%), Sertoli-Leydig cell tumor(8.3%), others(4.0%) were counted in order. 2. The mean age of sex cord-stromal tumor was 44.0 years and 8 cases(33.4%) of tumors over the age of 50.0 years, 13 cases(54.2%) over the age of 40.0 years. 3. Main initial symptoms were abdominal pain(37.5%), asymptomatic cases(25.0%), abdominal mass palpation(16.6%), irregular menstruation(12.5%) in order. 4. Management was surgery only(91.7%), surgery and chemotherapy(8.3%). 5. The mean disease free survival was 30.6 months.
Subject(s)
Female , Humans , Disease-Free Survival , Granulosa Cells , Gynecology , Hysterectomy , Incidence , Mesoderm , Obstetrics , Ovarian Neoplasms , Ovary , Sex Cord-Gonadal Stromal TumorsABSTRACT
Sex-cord stromal tumors of ovary account for 5~8% of all ovarian malignancies. This group of ovarian neoplasms is derived from the sex cords and the ovarian stroma or mesenchyme. Although they can occur in women of all ages, they tend to have peak incidence in those over age50. So they should be surgically managd with hysterectomy and bilateral salpingo-oophorectomy. The purpose of this study is to report the experience at Asan Medical Center, Department of Obstetrics and Gynecology, in 24 patients with ovarian sex-cord stromal tumortreated between May, 1989 and April, 1995. We analyzed the effect of histologic subtype, FIGO stage, age and management. The results were as follows: 1. In histologic subtypes, fibrothecoma(66.7%), granulosa cell tumor(20.8%), Sertoli-Leydig cell tumor(8.3%), others(4.0%) were counted in order. 2. The mean age of sex cord-stromal tumor was 44.0 years and 8 cases(33.4%) of tumors over the age of 50.0 years, 13 cases(54.2%) over the age of 40.0 years. 3. Main initial symptoms were abdominal pain(37.5%), asymptomatic cases(25.0%), abdominal mass palpation(16.6%), irregular menstruation(12.5%) in order. 4. Management was surgery only(91.7%), surgery and chemotherapy(8.3%). 5. The mean disease free survival was 30.6 months.
Subject(s)
Female , Humans , Disease-Free Survival , Granulosa Cells , Gynecology , Hysterectomy , Incidence , Mesoderm , Obstetrics , Ovarian Neoplasms , Ovary , Sex Cord-Gonadal Stromal TumorsABSTRACT
During the 6 year period, frorn May 1, 1989 to August 31, 1995, 40 cases of endometrial carcinoma were encountered at College of Medicine, University of Ulsan, Asan Medical Center. The purpose of this study is to investigate the patient's clinical characteristics and to correlate these findings with the there histopathologic results. The results were as follows : 1. There was an increasing tendency of endometrial carcinoma during 3-year time interval between May 1, 1989 and August 31, 1995. 2. Age distribution of the patients with endometrial cancer showed; 10% for the 31s ages<40, 27.5% for the 41.